Uji Aktivitas Sitotoksik Fraksi Daun Matoa (Pometia pinnata) dengan Metode Brine Shrimp Lethality Test (BSLT)

Matoa (Pometia pinnata) is parts of Sapindaceae family widely spread in tropical areas, especially Papua. Several studies mentioned the use its as antioxidants and contain phenolic compounds flavonoids. This study aim(s) to conduct a phytochemical screening test well cytotoxic for Pometia pinnata leaves fraction using BSLT method. The research series began with extraction process 96% ethanol, then fractionated three solvent variations: n-hexane, ethyl acetate, ethanol. Further, was carried out testing order see mortality rate shrimp larvae Artemia salina Leach. result showed that secondary metabolite on ethanol acetate were alkaloids, flavonoids, saponins, tannins, terpenoids meanwhile n-hexane contained terpenoids. results LC50 value 7029.10 ppm, 406.07 ppm 614.47 Thus, it could be said fractions classified toxic category, while non-toxic category.Key words: matoa; fraction; screening; cytotoxic.